Vitamin C is used in combination with your Microdosing cycle to enhance the therapeutic effects of psilocybin. We explain the benefits:
1. Bioavailability
Vitamin C Increases the bioavailability of psilocybin, by increasing the activity of the liver enzyme CYP450, which is involved in the metabolism of psilocybin (1) (2). This increases the amount of level of psilocybin that reaches the brain which leads to longer lasting and stronger experience
2. Cell Protection
Vitamin C acts as an antioxidant that can help protect cells from damage caused by harmful molecules called free radicals. Vitamin C helps to improve the healing and regeneration of cells. (3) Also Vitamin C supports the Immune system by enhancing the activity of white blood cells to fight off infections and protect against stressors which contribute to cell protection.
3. Reduce inflammation
There have been several studies that suggest supplementing with vitamin C improved symptoms of depression in individuals who were deficient in the nutrient (4). Vitamin C may help regulate levels of neurotransmitters such as serotonin and dopamine, which play a role in mood regulation. Also it has anti-inflammatory effects which may also be beneficial for individuals with depression, as chronic low-grade inflammation has been linked to the development of mood disorders. (5)
4. Reduce side effects
Vitamin C may help to protect the brain from some of the negative effects of psilocybin such as nausea, anxiety or paranoia by reducing oxidative stress in the brain. Reducing oxidative stress in the brain may have several benefits including improving brain function, reducing risk of neurodegenerative diseases and supporting overall brain health. (6)
1. "Metabolic fate of psilocybin in the rat," Journal of Pharmacy and Pharmacology, 1991
2. "In vitro evaluation of the effect of ascorbic acid on cytochrome P450 enzymes," Psychopharmacology, 2002
3. "Vitamin C: antioxidant and immunomodulator," Nutrition Reviews, 2002.
4. "The effect of vitamin C supplementation on symptoms of depression in patients with major depressive disorder: a randomized controlled trial," Journal of Affective Disorders, 2016.
5. Vitamin C supplementation reduces inflammation and oxidative stress in patients with major depressive disorder," Nutritional Neuroscience, 2018.
6. "Vitamin C modulates oxidative stress, neuroinflammation and neurodegeneration," Banerjee P et al., Journal of Neurochemistry, 2015.
4 healing Benefits of Vitamin C and Microdosing
Related Posts
Psilocybin and the Third Eye: Seeing Beyond Illusion
Psilocybin and the Third Eye: Seeing Beyond Illusion For centuries, mystics and medicine women have spoken about the third eye, a hidden faculty of perception beyond the five senses. Located between the eyebrows and often associated with the pineal gland, the third eye is considered the seat of inner vision, intuition, and higher truth. But why does it matter? Because when the third eye is closed, we live in a world of illusion, bound by ego, fear, and the endless distractions of low-frequency addictions. What Is the Third Eye? Spiritually, the third eye is the gateway to awakening. It is said to: Reveal the illusion of the ego, the false identity built on fear and separation. Unmask the power structures of society that profit from our disconnection. Show the ways we are kept asleep through addiction: sugar, alcohol, pornography, shallow beauty standards, endless consumption. Connect us to a higher frequency of consciousness, truth, love, and freedom. Scientifically, the third eye relates to the pineal gland, a small organ in the brain that regulates circadian rhythms and is sometimes referred to as our “receptor of light.” Modern neuroscience suggests psilocybin works not by directly activating the pineal gland, but by stimulating serotonin 5-HT2A receptors in the visual and prefrontal cortices. The effect is a state of expanded perception, visions, insights, and profound shifts in meaning-making. How Psilocybin Opens the Third Eye When psilocybin enters the body, it is converted into psilocin, which binds with serotonin receptors and increases connectivity between brain regions. This loosens the rigid grip of the default mode network, the seat of the ego. The result is a dissolution of boundaries: The ego’s illusions of control and separation fall away. Fear softens. Addictive patterns lose their hold. A new clarity emerges, not from the rational mind, but from the deeper wisdom of the soul. This is why indigenous Mazatec and Mixtec medicine women, curanderas, called the mushrooms niños santos — holy children. In ceremony, the mushrooms revealed the root causes of disease, whether emotional, physical, or spiritual. They helped people see what was hidden, heal what was suppressed, and restore harmony. Today, neuroscience describes the same process in clinical terms: psilocybin allows the brain to reset, to create new pathways, and to release old patterns of fear and trauma. Why Opening the Third Eye Matters We live in a time when society thrives on keeping the third eye closed. Distraction, overstimulation, consumption, these are not accidents, but systems designed to keep us disconnected from our truth. Opening the third eye means: Seeing through illusion: recognizing how fear and ego shape our decisions. Breaking cycles of addiction: to sugar, porn, alcohol, or beauty ideals that numb us. Awakening to higher truth: living from resonance, love, and authenticity rather than survival and conformity. Remembering who we are: not consumers, not victims, but conscious beings capable of vision, creation, and freedom. Quantum: A Tool for Awakening At Earth Resonance, we created Quantum as a psilocybin formula for deep awakening. It is designed for those ready to: Move beyond surface healing. Activate the higher centers of awareness. Open the third eye and step into clarity, vision, and purpose. Explore Quantum: your ally for awakening, vision, and third eye activation. An Invitation to See To awaken the third eye is to step out of illusion and into truth. It is to pierce the veil of ego and fear, and to remember that at your core, you are light. Psilocybin is not the only path, but it is a powerful ally in this awakening. The question is not whether the third eye can open. It is:Are you ready to see what has been hidden?
Learn more
Healing the Root Chakra with Psilocybin Microdosing
Healing the Root Chakra with Psilocybin Microdosing: A Scientific and Holistic Perspective The Root Chakra, or Muladhara in Sanskrit, has been described for thousands of years in Eastern philosophy as the foundation of human energy. It symbolizes safety, trust, and our basic right to exist. While this may sound abstract, modern neuroscience and trauma research increasingly affirm what ancient traditions have long taught: that unresolved fear and anxiety are stored not only in the mind, but also in the body. A Historic View Meets Modern Science Ancient yogic texts described the Root Chakra as the “seat of survival,” the energetic base that determines how safe we feel in the world. Today, psychology and neuroscience echo this idea. Research by Bessel van der Kolk (2014, The Body Keeps the Score) and more recent trauma studies show that traumatic experiences are encoded in both the nervous system and the brain, creating what scientists call “implicit memory.” This explains why the body can stay locked in fight-or-flight responses, even decades after the original event. When the Root Chakra is “blocked,” it is not just a metaphor. We now know that chronic stress and trauma correlate with increased activation of the amygdala (fear center), shallow breathing patterns, muscle tension in the lower body, and disrupted sleep. Psilocybin Research and the Body’s Root of Fear In the past decade, clinical research into psilocybin, the active compound in psychedelic mushrooms and truffles, has provided groundbreaking insights. Studies at Johns Hopkins University (Griffiths et al., 2016; 2022) and Imperial College London (Carhart-Harris, 2018; 2021) show that psilocybin-assisted therapy can significantly reduce anxiety, depression, and trauma-related symptoms. Psilocybin appears to temporarily reduce activity in the default mode network (DMN) of the brain, the system associated with rigid patterns of thought and self-referential fear. At the same time, it increases connectivity across brain regions, allowing suppressed memories and emotions to surface in a safe, recontextualized way. In other words: psilocybin creates a window of opportunity to revisit and release what has been locked in the nervous system, the very essence of Root Chakra work. Microdosing Psilocybin Truffles: A Contemporary Practice While high-dose psilocybin sessions attract most of the headlines, microdosing psilocybin truffles has quietly become a contemporary wellness practice worldwide. In 2025, more individuals are using microdosing not only for creativity and focus, but also to regulate anxiety, improve sleep, and heal from early abandonment trauma. At Earth Resonance, we have translated both ancient chakra psychology and cutting-edge science into structured microdosing protocols. These are not random experiments — they are carefully designed cycles: The Pre-Cycle – Preparing the body with immune-supportive supplements like Immuno Defense+ and superfoods to stabilize the nervous system. The Microdosing Cycle – Precision-based use of psilocybin truffles to gradually unlock stored emotional patterns and enhance neuroplasticity. The Integration Cycle – Anchoring new patterns with targeted supplements such as Harmony & Calm, while using journaling, breathwork, and grounding practices. This three-phase approach ensures that microdosing is not just an isolated practice, but a complete transformation journey that works on both body and mind. Practical Ways to Heal the Root Chakra Scientific evidence increasingly supports holistic practices that were once considered “alternative.” For Root Chakra healing, both research and tradition suggest: Grounding in the body: Breathing exercises, yoga, walking barefoot (shown to reduce cortisol and inflammation through “earthing”), pelvic floor relaxation. Re-establishing safety: Supportive therapy, trusted relationships, and guided psychedelic-assisted healing. Conscious reprogramming: Affirmations, cognitive reframing, and inner child work, which have shown measurable effects in neuroplasticity research (Davidson & McEwen, 2020). How Do You Know Healing is Taking Place? Indicators of Root Chakra balance are not mystical — they are physiological and psychological: Lower baseline cortisol levels (less stress reactivity). Improved sleep cycles and heart-rate variability. A deeper breath and greater presence in the body. Reduced anxiety, less compulsive control, and more trust in life. These outcomes have been consistently observed in studies on psilocybin-assisted therapy and are mirrored in the feedback from participants in Earth Resonance protocols. Earth Resonance: Bridging Science, Nature, and Transformation At Earth Resonance, we combine ancient wisdom with 21st-century science. Our psilocybin truffle microdosing protocols are supported by natural supplements that work in synergy with the nervous system. The result: a grounded, research-informed path to healing fear, anxiety, and trauma from the root. Whether you are seeking freedom from survival patterns, a stronger sense of safety, or deeper presence in daily life, Earth Resonance offers a complete system that supports healing from the Root Chakra upward. Discover more: Explore our microdosing protocols and learn how psilocybin truffles, microdosing, and supplements can help you heal from the root and step into trust, flow, and resilience.
Learn more
Boundaries as Medicine: How saying No Heals the Nervous System
How Microdosing can Help to Set Boundaries? In a world that often praises productivity, perfection, and people-pleasing—especially in women—setting healthy boundaries can feel unfamiliar, uncomfortable, or even unsafe. Yet from a psychological and nervous system perspective, boundaries are essential for emotional health, identity, and long-term wellbeing. This blog explores why so many women struggle with saying “no,” how this pattern is wired into our nervous systems, and how microdosing psilocybin can gently support the process of reclaiming healthy boundaries from the inside out. Why Do So Many Women Struggle with Boundaries? From a young age, many women are conditioned to value external approval over internal safety. This shows up as:• Saying yes to avoid conflict• Prioritizing others’ needs over their own• Feeling guilty for resting or asserting needs• Suppressing discomfort to keep the peace These patterns are not personality flaws. They’re adaptive survival strategies—especially for women with trauma histories, emotionally immature caregivers, or environments where saying “no” came with consequences. Psychologist Dr. Gabor Maté explains this through the lens of authenticity vs. attachment. When we’re young, if our authentic self-expression threatens our sense of belonging or love, we learn to abandon authenticity in favor of attachment. This shows up in adulthood as porous boundaries, overgiving, and chronic dysregulation. What Are Healthy Boundaries, Really? Healthy boundaries are not rigid walls or defenses. They are energetic and emotional agreements that define what’s okay and what’s not okay for us—physically, emotionally, mentally, and spiritually. They help us:• Protect our time and energy• Feel safe in relationships • Maintain self-respect • Honor our inner yes and no• Restore autonomy after trauma And perhaps most importantly: they regulate the nervous system by removing us from unsafe dynamics that keep us in fight, flight, or freeze. The Role of the Nervous System in Boundary-Setting If you find yourself saying “yes” when you mean “no,” you’re likely not making a cognitive decision—you’re having a nervous system response. For example: • Saying yes because your body tenses in fear when you imagine conflict • Going along with something because your heart races when you consider asserting yourself• Fawning or freezing in the face of pressure This is where healing must go deeper than mindset work. We need to work with the body, not against it. How Microdosing Can Help You Reclaim Boundaries Microdosing psilocybin—taking a sub-perceptual dose of psychedelic truffles—offers a powerful, natural tool for nervous system healing and boundary restoration. Here’s how: 1. Nervous System Regulation Microdosing can support parasympathetic activation (rest and digest), helping you shift out of chronic survival states. A regulated nervous system makes it easier to recognize when something feels off—and to respond instead of react. 2. Increased Emotional Awareness Women often override subtle signals from the body. Microdosing enhances interoception (the ability to feel internal sensations), allowing you to more clearly sense: “This doesn’t feel right,” or “My body says no.” 3. Reduced People-Pleasing & Fawning Through its effects on the Default Mode Network, psilocybin reduces rigid thinking and people-pleasing loops. This allows new neural pathways to form—ones rooted in self-trust, not fear. 4. Empowerment Through Pattern Recognition Microdosing enhances cognitive flexibility, which supports recognition of old, inherited patterns (like perfectionism or emotional caretaking), so you can begin choosing differently. 5. Integration & Intentional Practice When used in combination with coaching, journaling, or somatic exercises, microdosing becomes a powerful catalyst for behavioral change. It can help you actually implement the boundaries you’ve intellectually understood for years. A Feminine Approach: Boundaries as Self-Love In our work with women through guided microdosing journeys, we see a common theme: when women begin listening to their bodies again, they stop abandoning themselves. They no longer say “yes” when they mean “no.” They stop betraying their energy for validation. They remember that their needs are not a burden, but a compass. Saying no becomes not a rejection of others, but a radical act of self-respect. Final Thoughts: Your No is a Spell In feminine wisdom traditions, boundaries are sacred. They are the energetic architecture of sovereignty. When you say no to what drains you, you say yes to your truth, your softness, your expansion. Microdosing is not a quick fix, but it is a beautiful, powerful ally on the path back to your body, your voice, and your deep knowing. Ready to Begin Your Boundary-Setting Journey?Start Microdosing with our Therapeutic Microdosing Protocol Trinity. CLICK HERE
Learn more